Many weapons appear in the Simpsons.
Homer Simpson buys one in the episode "The Cartridge Family". The weapon deeply worries Marge as she is afraid that Homer will shoot one of his own family, which Homer replies with, "TV said that?". Later when Homer says he will get rid of it, he actually hides in the vegetable crisper, as a means to hide it from Bart. And Marge leaves him as a result. After she leaves, Homer says "This gun has cost me everything, everything exept my precious gun." After a failed NRA meeting, Homer falsely claims that he has gotten rid of the gun again when he comes to apologise to Marge and take her back home. However, when Snake robs the motel, he reveals he still has the gun. after Snake leaves, Homer asks Marge to get rid of it as he would only lie again. However the last scene shows that she keeps the gun.
Homer uses it to shoot a cigarette in the episode "Smoke on the Daughter".
Bolt Action Rifle
Moe Szyslak is variously seen aiming a sawed-off shotgun at regulars to his bar.
In "$pringfield (Or, How I Learned to Stop Worrying and Love Legalized Gambling)", Homer uses one to defend him and the kids from the "bogyman".
In "Treehouse of Horror III" Homer uses a shotgun to dispatch the Zombie Ned Flanders - "He was a zombie?" The shotgun used was based of the model 1887.
Thompson Submachine Gun
Grampa in his war days has something that looks like a thompson in the Flying Hellfish unit in "Raging Abe Simpson and His Grumbling Grandson in "The Curse of the Flying Hellfish"".
Moe Szyslak says with a few 'minor' adjustments, you can turn one gun into 5 guns during the episode "The Cartridge Family".
SMG (Sub Machine Gun)
Sideshow Bob wields one and often tries to kill Bart with it.
Homer wields one in the "Whacking Day".
This is Bart's essential weapon, which he always carries in his back pocket, parodying Dennis the Menace. His ammunition ranges from cats to small rocks.
Used in most "Itchy & Scratchy" episodes.
In "Sideshow Bob's Last Gleaming", Sideshow Bob tries to destroy Springfield with a nuclear bomb, but it is dud.
RG-6 Grenade Launcher
Bart used this during a firing range exercise under the suggestion of the instructor in "The Secret War of Lisa Simpson"
SEC agents wields several in "The Ziff Who Came to Dinner".
Lisa tries to use it in the episode The Secret War of Lisa Simpson, but it was stuck in auto-fire and she coudn't stop shooting it.
Sideshow Bob tries to kill Bart with a machete in "Cape Feare".
After Homer gets crazy without beer and TV in Treehouse of Horror V segment "The Shinning", he tries to kill his family with an axe. Groundskeeper Willie is also killed three times by an axe during the episode.
Hand Minigun appears in "Treehouse of Horror XVIII" segment "Mr. & Mrs. Simpson", operated by Homer.