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Trixie Stemple (neé Simpson) was the daughter of Rupert Simpson and Winifred Running Goat. Her siblings were named Prudence, Galston, Ivy and Garwood. Her husband was named Gaylord Stemple and their children were named Paco, Caleb and Vic.

Trixie's marriage to Gaylord Stemple joined the Burns and Simpson families together through Gaylord's sister Clarice. Trixie is the great-great-great-great grandaunt of Homer Simpson.

Appearances