The opening sequence features the Simpson family as candy bars on Halloween, trying to avoid getting eaten.
The Exor-Sis: Maggie gets possessed by an evil demon.
Coralisa: Lisa, along with Snowball V, discover a creepy/perfect version of her family in an alternate universe.
MMM... Homer: Homer cannibalizes himself after he runs out of food while Marge and the kids are away from home.
In a CGI short known as "The Sweets Hereafter", it is Halloween night in Springfield as trick or treating is going on, and a bowl of candy is in front of a house. Suddenly, the candy comes to life, where Barterfinger is afraid that someone might take him, but Marge Bar comforts him and tells him not to worry, because he is always the last one to be taken. Oh Homer! tells Barterfinger that even the boxes of stale raisins get taken before him, but mistakes Barterfinger's name for "Butterfinger".
As Nelson's Crunch and Kirkish Taffy get taken, Apple Lisa discovers that no trick or treaters ever wants the apple, because they must be afraid that there is a razor blade inside it. Barterfinger knows that is the reason, and Marge Bar tells Apple Lisa that maybe they get apples only when they are dipped in caramel, which makes Apple Lisa disgusted at the fact. Suddenly, Shauna reaches for the candy, but Oh Homer! avoids getting taken by letting Senior Mints get taken instead, and asks Oh Homer! where is he going. Oh Homer! tells Senior Mints that he is going somewhere else.
As Senior Mints gets taken by Shauna, Oh Homer! tells Senior Mints that change is always hard. Shauna then opens up the box of Senior Mints and starts to eat them down her throat, to which Senior Mints freaks out and even gets scared about the cigarette breath that she has.
The next day, as the citizens of the house are taking down their Halloween decorations, the bowl of candy is now almost empty and now the Simpson family are the only ones left in the bowl. One of the house's citizens grabs the bowl, and while walking with it to a high shelf, Marge Bar tells the rest of her family that they made it through the night, much to their glee.
After the bowl is placed onto a higher shelf (between a plate of Christmas cookies and a basket with a chocolate easter bunny), a chocolate easter bunny tells the family that they are on a high shelf where people will forget about them forever, just like himself. As the chocolate easter bunny sadly asks himself why won't people take him, Oh Homer! comforts him, takes a piece of the bunny's ears, and eats it. However, Marge Bar tells Oh Homer! not to do it, but Oh Homer! tells her to not be silly, because chocolate doesn't feel anything, so he takes another piece of the bunny, much to the bunny's horror. Apple Lisa worriedly tells Oh Homer! that she can't listen to the bunny's horror, so Oh Homer! eats the bunny's mouth off in order for it to be silent.
Eventually, the Simpsons choose to eat the entire chocolate easter bunny for themselves. The camera then pans to the wall, where it has the words "The Simpsons Easter Special" (written with Peeps, jelly beans and other easter treats). But, because of the Simpsons eating the chocolate bunny, the chocolate splatters onto the wall, thus covering up the words, followed by some dark chocolate to spell out "Treehouse of Horror XXVIII" over the milk chocolate.