The introduction in Bart's nightmare is based on Rod Serling making the introduction to the Twilight Zone episodes.
During Homer's nightmare, Bart and Lisa are watching Johnny Carson.
At school, Seymour Skinner sings "Michigan Rag" for Bart Simpson on the PA system, which is from the Looney Tunes' episode One Froggy Evening.
Snowball II looks like Daffy Duck breathing flames from the cartoon of Duck Amuck.
Charlie Brown and friends are seen trick-or-treating outside the Simpson home.
A monkey's paw that grants wishes is based on "The Monkey's Paw" horror story by W.W. Jacobs.
Bart's nightmare is largely based from the "It's a Good Life" segment of The Twilight Zone.
During Lisa's nightmare, when the Simpsons are about to board the plane, the Moroccan police stop them by aiming pistols at them in the kneeling position, then lift up Homer's shirt to find smuggled items taped to his abdomen, parodying the opening scene of Midnight Express.
In Homer's nightmare, Mr. Burns is humming "If I only had a brain" from The Wizard of Oz while removing Homer's brain and the near-quote "You clinking, clattering, cacaphony of colligenous cogs and camshifts!" was originally used as an insult to the Tin Man.
This is the only THOH episode where titles of the segments don't appear in.
This is the only Halloween episode that does not have titles for the segments, where as fans have come up with them.
Nancy Cartwright, the voice of Bart, also played a character in the It's a Good Life segment from the Twilight Zone Movie, which the second segment is parodying.
The DVD commentary of the episode reveals that the names of Kang and Kodos are from Star Trek.
According to Jim Reardon, the ending in the Monkey's Paw, where Flanders got a castle, was a last minute edition.
The Pentagon appears as a shopping center in "Monkey's Paw".
This is the first Treehouse of Horror to have the cast's names changed due to Halloween e.g. Bat Groening.
The credits and font is the same as the original Treehouse of Horror, but have different notices.
So far the only THOH episode with no deaths (unless one counts Mr. Burns' head being separated and placed onto Homer's head as a death).
At the end of the Simpsons credits the Gracie Films logo in a Halloween special does not have the scream, but have the organ.
In Another Simpsons Clip Show, they remember Moe's prank call, even though all of the stories are in the form of nightmares by Lisa, Bart, and Homer.
When Mr. Burns sews Homer's brain back into his head, he originally said, "Quit complaining! This way I don't have to waste money on morphine! Well, Smithers, you were right — he was not dead. I guess I owe you a Coke." In the final version, Burns says, "Will you quit your complaining?"; Smithers adds, "Sir, he is alive.", then Burns says, "You're right, Smithers. I guess I owe you a Coke."
Although the episode itself (and the second segment where Bart is shown to read minds) is not canon, Bart being able to read minds in itself was later alluded to in The Boy Who Knew Too Much, where Skinner mentally threatened Bart.