Jeffery Albertson makes his first appearance in this episode. The Android's Dungeon also makes its first appearance.
First discovery of Radioactive Man's freak accident.
Otto's idea for a comic book (Busman, a man who drives a bus by day and fights vampires by night) was made into a comic in the Simpsons Comics.
Hint to Springfield being located in either Michigan or California: When Bart recycles an empty cola bottle at the Kwik-E-Mart, he says "I need the dime". Michigan and California are the only states that have a 10 cent bottle deposit.
The Radioactive Man black and white serial was sponsored by Laramie Tobacco, to which Fallout Boy is told he is too young to smoke Laramies. Moments after the sketch ends, Buddy Hodges, the actor who played Fallout Boy is seen holding a cigarette.
Patty and Selma had higher and more feminine voices before they took up smoking.
The convention's emcee telling the attendees not to ask Buddy Hodges about the sordid details of Dirk Richter's final year alive and mysterious death could have referred to the still-disputed death of George Reeves. The bordello remark may have also been a reference to the brutal murder of Bob Crane in 1978, which remains unsolved today. The cast of Hogan's Heroes stated that in public and at fan conventions Crane's death was the biggest subject they had to deal with.
Martin's remaining Vulcan ear is green (Vulcan blood is green, but the skin would only be green-tinged). It may have been intended to be a goblin or green elf ear and the Vulcan reference was added later.
The issue of Radioactive Man that took place before Fallout Boy became his ward was actually #3, not #9.
The scene at Krusty Burger where Bart considers getting a part-time job is a reference to The Wonder Years. The actor Daniel Stern guest starred as Bart's adult voice, just like he did for the adult voice of Kevin, the main character of this show.
Another reference to The Wonder Years : Milhouse is a caricature of Paul Pffeifer, a character from this show.
The main plot of Bart, Milhouse and Martin fighting over the comic book and driven to the point of paranoia is based on the 1948 film The Treasure of the Sierra Madre.
The scene where Milhouse's sleeve is ripping is a reference to Saboteur.
When a repeat of this episode aired in 1992, a brief tribute to The Cosby Show aired following the end credits. The Cosby Show ended on April 30, 1992, and the tribute featured Bart and Homer discussing the quality of the show and its importance to Bill Cosby.