The Slaughterhouse is a barn-themed steakhouse that operates in Springfield. The interior is decorated with hanging steer carcasses and a fountain of blood, and customers choose a cow for their steak (or a glass of milk) which is slaughtered right in front of them. Everything on the menu contains meat and the menu itself is a whole chicken pounded flat. It also featured a neon sign that depicted a cowboy graphically decapitating a steer with a chainsaw. Those who work at the restaurant wear black pants and a black bow-tie/necktie, as well as a crimson dress shirt.
The largest steak on the menu is 72 oz. New York-style Sirloin Steak, but a 16 lb. Tenderloin steak called Sir Loin-A-Lot is available on special request. Only two people have eaten it successfully: Red Barclay and Tony Randall.
The restaurant is controversial amongst vegetarians for its overly pro-meat attitude and a group (including Lisa Simpson) were scheduled to protest. Ironically, Lisa ended up unwittingly convincing the family to go when explaining her plans to protest. Aside from this, it is also implied that it may have had poor preparation of food, as Red Barclay had died from beef poisoning and Dr. Hibbert (who previously stated he had stock on that restaurant) assuring everyone it was from "a different meat restaurant." The Waiter also implied that eating massive amounts of beef from the restaurant would gradually kill any customers when supplying Marge with a body bag for Homer.
Aside from obviously serving steak, Red Barclay implies that they served lamb, as when Homer rudely challenged him to the Sir Loin-A-Lot challenge, Barclay said that he had just finished a whole lamb, but that wouldn't stop him from accepting the challenge.
Homer met Red Barclay there and challenged Red to a beef-eating contest. Red won but suddenly died of beef poisoning, leaving behind a truckload of artichokes and migrant workers to be delivered to Atlanta. As Homer overheard two other truckers talking about Red, he decided to drive Red's truck to Atlanta.