Busman opens with a dialogue about The Desert's desolate nature. It has been years since The Nuclear War and Mutant Vampires are a constant threat. Busman escorts some passengers (The Floozy, The Lush, The Bounty Hunter and The Missionary Lady) in his School Bus at price of various goods. He picks up a stranded Mr. Burns and Smithers. While stopping into The Trading Post Busman meets a mysterious woman looking for a ride. After explaining how her axe (guitar) broke after smashing it over her managers head Busman sympathizes for her situation and offers he a free bus ride. While driving through the desert the bus is attacked by Mutant Vampires. The passengers help Busman ward the vampires away. When Busman is caught from behind and the mysterious woman saves him by stabbing the vampire with the her broken fretboard. The bus reaches Garlicville and drops off the passengers, except for the mysterious woman. Busman asks where she wants to go and she replies 'wherever you're going'. They ride off to the sunset and she says to Busman that he can call her Busbabe.