This episode shows that Springfield is located in the middle of the United States. This could be also deducted from "Much Apu About Nothing". Both chapters suggest that the Springfield from USA which corresponds to the fictional Springfield in The Simpsons is the one from Colorado. However, Matt Groening has revealed that the town was named after Oregon's Springfield, and in Eternal Moonshine of the Simpson Mind, it is shown that The Simpsons's Springfield is the one from Illinois. This contradictory evidence might suggest that Springfield is just a fictional place with no precise location in the Simpsons Universe, as one of the many coherence issues in the show.
Mr. Smithers comes out as a homosexual in this episode.