Snake Rice Wine is a type of wine that Homer Simpson and Kumiko's father had while in a Chinese pub. It's wine made from rice with a snake in the bottle. After drinking it, they began to have a vision. They were followed by spirits, one of them named No Face.
Snake wine is an alcoholic beverage produced by infusing whole snakes in rice wine or grain alcohol. The drink was first recorded to have been consumed in China during the Western Zhou dynasty and was medicine that never worked. Real medicine in ancient China had herbs and no animal in them.