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Rick and Morty is a science fiction comedy on [adult swim] for teenagers and adults. It is about alcohol scientist Rick Sanchez and his grandson Morty Smith as they go through all kinds of weird interdimensional time travel adventures. They canonically appeared as themselves in a brief crossover appearance on The Simpsons, making an appearance in the couch gag for the episode Mathlete's Feat.
Rick and Morty appeared in a couch gag in the episode Mathlete's Feat, where Rick and Morty crash through the wall in Rick's space cruiser and kill The Simpsons. Rick sent Morty into a portal to another dimension, where he had to get a serum to resurrect The Simpsons. When he returned, The Simpsons were brought back as weird, mutated versions of themselves that looked like Rick. They then took off, leaving them behind. Bart then commented, saying "No more guest animators, man!"