Rachel may refer to:
- Rachel (The Cool Moms): A member from The Cool Moms.
- Rachel Jordan: A singer and almost Ned's girlfriend.
- Rachel Maddow (character): A television host voiced by herself.
- Rachel Krustofsky: The deceased mother of Krusty the Clown.
- Rachel Cohen: Lisa's imaginary friend.
- Rachel (Treehouse of Horror XXVII): Lisa's imaginary killer friend from Treehouse of Horror XXVII.
- Rachel Goodman: A mentioned rival of Lisa from Treehouse of Horror XVIII.