Panama is a country of Central America.
- Episode – "Boy-Scoutz 'n the Hood"
- Episode – "Two Bad Neighbors"
- Episode – "Mobile Homer" (Mentioned in song during credits)
- The first episode of The Simpsons aired on December 17, 1989, just three days before Operation Just Cause or the U.S. Invasion of Panama that toppled down General Manuel Noriega; so it is reasonable for for Barbara Bush to mention about the dictator since it was her husband, George H.W. Bush (POTUS 41) that ordered the invasion in response to killing of a U.S. Marine Lieutenant. Noriega died on May 29, 2017.