| Ms. Samson|
|Relatives|| Husband: Mr. Samson|
Son: Gerald Samson
|First Appearance||Moe Baby Blues|
Mrs. Samson is the mother of Gerald Samson, Maggie's arch enemy. She has unibrow just like her son. Not much is known about her. She is also a member of Midday Mommies mother parents meeting group. Mrs. Samson has a very different appearance in the Bart Simpson comic story, "The Maggie & Moe Mysteries!"
- Episode – "Last Tap Dance in Springfield"
- Episode – "Moe Baby Blues" (Cameo at Maggie's birthday party)
- Episode – "Pranks and Greens"
- Comic book – The Maggie & Moe Mysteries!