When Maggie comes down with the chicken pox, Homer actually takes some advice from Flanders and holds a "pox party" so his friends could have their kids infected. After one too many "Marge-aritas", Kirk and Luanne van Houten decide to get back together. However, Milhouse realizes they're too interested in each other and not interested in him, so he tries to breaks them up by planting a bra in his parents' bedroom. One problem: Luanne discovers it's Marge's bra, which leads to Homer and Marge breaking up yet again...
Inspired by Flanders' suggestion of purposely exposing the boys to the chicken pox, Homer invites all the neighborhood kids over to the Simpson house for a "pox party" (at fifteen bucks a head). However, he ends up catching it himself, having no childhood immunity. One good thing comes of it, though: Milhouse's folks reconcile.
Or so it seems. However, Milhouse feels neglected because his parents aren't fawning over him as they once did, competing for his love. Milhouse schemes to break up his parents again, and enlists both Bart and a plot borrowed from The O.C. The boys leave a bra conspicuously located in Kirk's bed--unfortunately, it's one of Marge's. Luann thinks Marge is having an affair with her husband, and soon she has Homer questioning his wife's fidelity. An argument ensues, and Bart realizes he may have split up his own parents instead of Milhouse's.
Marges makes Bart confess to what he did. Bart schemes to reunite them by pretending to fall off Springfield Gorge into a river, using a dummy--but Milhouse's poor eyesight queers the deal, and Bart ends up really taking the plunge. Homer leaps into the rapids and strangles Bart after Bart confesses about the bra and rescues Bart, and through a little trust, Marge saves them both from going over the falls. The Simpsons reconcile, once safely on the bank. Milhouse, not wishing to live in a world without his best friend, leaps over the cliff. Marge worriedly asks if he can swim. "What do you think?" asks Bart.