- SNPP Applicant
- SNPP Clerk
- SNPP Employees
- SNPP Guard
- SNPP Security Guard
- STEM
- SUV
- SUV Superstore
- SWAT Agent
- SWAT Leader
- S Money
- Sab Shimono
- Sabertooth Meadow
- Sabine Bohlmann
- Sacagawea
- Sacha Baron Cohen
- Sad Eyes
- Sad Girl
- Sad Grand-Dad Whiskey
- Sad Kid
- Sad Kid's dad
- Sad Kid's mom
- Saddlesore Galactica
- Saddlesore Galactica/Appearances
- Saddlesore Galactica/Credits
- Saddlesore Galactica/Gags
- Saddlesore Galactica/Gallery
- Saddlesore Galactica/Quotes
- Saddlesore Galactica/References
- Sadgasm
- Sadruddin Mahbaradad
- Safari Casino
- Safety Dance
- Sailor
- Sailor Kid
- Saint Eleutherius of Nicomedia
- Saint Joseph
- Saint Patrick's Day
- Saint Sebastian's School for Wicked Girls
- Sakatumi
- Saks Fifth Grade
- Sales Coordinator Relative
- Sally Circle in Rectangu-Land
- Sally Martinez
- Sally Stevens
- Saloon Bartender
- Salsa mix version of Everybody Hates Ned Flanders
- Salsiccia
- Salt Doodles
- Sam (Postcards from the Wedge)
- Sam (barfly)
- Sam (barfly)/Gallery
- Sam (disambiguation)
- Sam (senior)
- Sam Grinberg
- Sam Malone
- Sam McMurray
- Sam Monroe
- Sam Munroe
- Sam Neill
- Sam O'Neal
- Sam Simon
- Samantha Stankey
- Samantha Stankey/Gallery
- Samba
- Samoa
- Samson Family
- Samuel Mason
- Samuel Morse
- Samuel T. Duff
- San Diego Comic-Con
- San Diego Comic Fest couch gag
- Sancho Hernandez
- Sandals
- Sandeep Nahasapeemapetilon
- Sandra
- Sandra (Game Done Changed)
- Sandra (Homerpalooza)
- Sandra Bullock
- Sandra Schwittau
- Sandwich Delivery Guy
- Sandwiches Are Forever
- Sandwiches Are Forever/Appearances
- Sandwiches Are Forever/Credits
- Sandwiches Are Forever/Gallery
- Sandwiches Are Forever/Quotes
- Sandwiches Are Forever/References
- Sandy
- Sandy Beach
- Sane Planning, Sensible Tomorrow
- Sanjay's House
- Sanjay Nahasapeemapetilon
- Sanjay Nahasapeemapetilon/Gallery
- Santa's Little Helper
- Santa's Little Helper's Brother
- Santa's Little Helper's Siblings
- Santa's Little Helper/Gallery
- Santa's Little Helper Short couch gag
- Santa's Little Hybrid
- Santa's On His Way
- Santa's Village
- Santa Baby
- Santa Claus
- Santa Homer (chimney version)
- Santa School
- Santina Quackenbush
- Sapphire Lounge
- Sapphire Lounge Guy
- Sappho of Lesbos
- Sara
- Sara (Student)
- Sara Chase
- Sara Gilbert
- Sara Sloane
- Sarah
- Sarah Drew Linscott
- Sarah Michelle Gellar
- Sarah Plain & Tall
- Sarah Silverman
- Sarah Silverman (character)
- Sarah Werner
- Sarah Wiggum
- Sarah Wiggum/Gallery
- Sarcasm Detector
- Sardine Queen
- Sardonicus
- Sascha Spuckler
- Sasha
- Sasha Reed
- Sasha is a Massive Success
- Sashi Nahasapeemapetilon
- Sashimi Bart!
- Sashimi Bart!/Appearances
- Sashimi Bart!/Credits
- Sashimi Bart!/Gallery
- Sashimi Bart!/Quotes
- Sashimi Bart!/References
- Sassy Madison
- Sassy Madison Theme Song
- Sassy Madison Train Tag
- Satan's Anvil
- Satan's Path
- Satans Funhouse
- Saturday Morning I&S
- Saturday Night
- Saturdays of Thunder
- Saturdays of Thunder/Appearances
- Saturdays of Thunder/Credits
- Saturdays of Thunder/Gags
- Saturdays of Thunder/Gallery
- Saturdays of Thunder/Quotes
- Saturdays of Thunder/References
- Saturn (car)
- Saucer-men
- Saudi Arabia
- Saul Bellow
- Saul Bernstein
- Sauna User 1 (couch gag)
- Sauna User 2 (couch gag)
- Sauna User 3 (couch gag)
- Sauna couch gag
- Save Hitler's Brain
- Savin' Those Babies
- Sax on the Beach
- Saxophonist
- Saxophony!
- Saxophony!/Appearances
- Saxophony!/Credits
- Saxophony!/Gallery
- Saxophony!/Quotes
- Saxophony!/References
- Say Hello to My Little Friend...Scarface!
- Say Hello to My Little Friend...Scarface!/Appearances
- Say Hello to My Little Friend...Scarface!/Credits
- Say Hello to My Little Friend...Scarface!/Gallery
- Say Hello to My Little Friend...Scarface!/Quotes
- Say Hello to My Little Friend...Scarface!/References
- Say Your Prayers
- Scam Wow!
- Scam Wow!/Appearances
- Scam Wow!/Credits
- Scam Wow!/Gallery
- Scam Wow!/Quotes
- Scam Wow!/References
- Scammer and Z-Dog
- Scammer and Z-Dog' Rap
- Scar Trek: The Next Laceration
- Scarecrow
- Scared Tentless
- Scared Tentless/Appearances
- Scared Tentless/Credits
- Scared Tentless/Gallery
- Scared Tentless/Quotes
- Scared Tentless/References
- Scared at Snake Canyon
- Scaredy Cats
- Scaredy Cats/Appearances
- Scaredy Cats/Credits
- Scaredy Cats/Gallery
- Scaredy Cats/Quotes
- Scaredy Cats/References
- Scarlet Tanager
- Scary Movie
- Scary Movie/Appearances
- Scary Movie/Credits
- Scary Movie/Gags
- Scary Movie/Gallery
- Scary Movie/Quotes
- Scary Movie/References
- Scary Stories
- Scary Stories/Appearances
- Scary Stories/Credits
- Scary Stories/Gags
- Scary Stories/Gallery
- Scary Stories/Quotes
- Scary Stories/References
- Scary Vultures
- Scenes from the Class Struggle in Springfield
- Scenes from the Class Struggle in Springfield/Appearances
- Scenes from the Class Struggle in Springfield/Credits
- Scenes from the Class Struggle in Springfield/Gags
- Scenes from the Class Struggle in Springfield/Gallery
- Scenes from the Class Struggle in Springfield/Quotes
- Scenes from the Class Struggle in Springfield/References
- Scent of a wookiee
- Scheme Supreme
- Scheme Supreme/Appearances
- Scheme Supreme/Credits
- Scheme Supreme/Gallery
- Scheme Supreme/Quotes
- Scheme Supreme/References
- School's Out (song)
- School Apple Pick
- School Dance
- School Day
- School Photographer
- School Song (Mathlete's Feat)
- School of Hard Knockers
- Schrödinger's Bat
- Schuman Farms
- Science
- Science for Leader Lovers
- Sciencewater
- Scoey (Music Conductor)
- Scoey’s killer
- Sconewall Bakery
- Scorpio (song)
- Scorpio Family
- Scotland
- Scott Alberts
- Scott Bakula
- Scott Christian
- Scott Greenberg
- Scott Muller
- Scott Thompson
- Scott Weingarten
- Scottish Rioter
- Scotty Boom
- Scout Manager
- Scout Spuckler
- Scrabble Couch Gag
- Scrabble couch gag
- Scrap City
- Scraps
- Scraps (The Computer Wore Menace Shoes)
- Scraps (Weekend at Burnsie's)
- Scrat
- Scratchem
- Scratchtasia
- Scratchy
- Scratchy Jr.
- Scratchy couch gag
- Scratchy mascot
- Screamapillar
- Screamatorium Worker
- Screaming Monkey Medical Research Center
- Screaming Woman
- Screams from a Mall
- Screamville
- Screenless
- Screenless/Appearances
- Screenless/Credits
- Screenless/Gags
- Screenless/Gallery
- Screenless/Quotes
- Screenless/References
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