The pig that Homer roasts and Lisa blasts into the air, flying over the nuclear power plant, is a direct reference to the cover of the Pink Floyd album Animals, which shows a pig flying over London's Battersea Power Station.
I Spit on Your Grave, a notorious exploitation film, is listed on the billboard for the drive-in cinema.
Apu mentions the song Live and Let Die sung by Paul McCartney and his band Wings, but he mistakenly refers to it as "Live and Let Live", being corrected by Paul.
Numerous references to The Beatles are present in the episode. Apu claims to have met Paul during the Maharishi period. The Beatles' visit to this guru in India was a big media story in 1967. Apu then claims to have been called "The Fifth Beatle" (mispronouncing it to rhyme with "Seattle"), a claim which Paul does not seem to agree with. The way Apu pronounces Beatles is a reference to how the antagonists in the movie Help! say it.
Apu plays and sings Sgt. Pepper's Lonely Hearts Club Band off-key on the tabla.
Lisa's remark, "Wow! Paul McCartney. I learned about you in history class", is a joke about the enormous cultural importance of the Beatles.
When Linda McCartney says "whenever we're in Springfield, we like to spend time in Apu's garden in the shade!" paraphrasing a lyric from the song "Octopus' Garden" (from the album Abbey Road).
The version of "Maybe I'm Amazed" that plays over the end credits is an original mix by the Simpsons staff that, when played backwards, contains snippets of Paul McCartney reciting a recipe for lentil soup – a throwback to an earlier gag. The recited recipe in forward speed can be found on the "Extras" section on Disc 1 of The Simpsons: Complete Season 7.
One of the backwards snippets says "Oh, and by the way, I'm alive." - a reference to the Paul is dead conspiracy theory.
The lamb chop changes color when it flies into Homer's mouth.
Biology animals are usually long dead.
It seems unlikely that a second grade class would be trusted with scalpels.
A girl which looks the same as Sherri and Terri appears in Lisa's class. This could possibly be the third "twin", but Sherri and Terri are in Bart's class, not Lisa's. It is possible that Sherri and Terri's sister was held back twice.
The cattle in "Meat and You" have horns; steers have their horns excised after castration.
The barbecue takes place in the Simpsons' backyard, and yet Bart's treehouse is nowhere in sight.
Strangely, Apu attends Homer's all-meat barbecue, even though he is a revealed to be a vegan at the end of the episode.
Homer's grill has knobs on it, like a gas grill, but he uses lighter fluid to get it started and it has no gas tank.
Lisa leaves the house without closing the door, and yet a slamming door is heard.
Apu calls himself a vegetarian, but later states that he doesn't eat any animal products. This would make him a vegan, not a vegetarian.
There are trees on the roof of the Kwik-E-Mart, and yet they are never visible in other episodes.
Neither Homer nor Lisa pays for the tofu dog that Lisa ate. It is likely that Apu didn't mind, seeing as how he is a family friend to the Simpsons.