This is the second episode in which Matt Groening, creator of the show, has guest-starred as himself. He last appeared in Season 15's "My Big Fat Geek Wedding," where he was signing autographs. In this episode, he is seen loading his truck with Bongo Comics, his own line of comic books, while saying how rich he is.
When Matt Groening is loading the comics on his truck, the back of his jacket shows the Simpsons family.
At the movie studio, one of the posters is for a movie called Welcome Back, Potter. This is a parody of the movie/book series Harry Potter and the 1970s sitcom Welcome Back, Kotter.
This is one of the few episodes where they bleep strong curses.
The villain in the Everyman film looks exactly like the Lizard, one of the villains of the comic book hero Spider-Man.
Some of the posters in the movie theater were references to real movies. Namely, Alvin and the Chipmunks Get Rabies was a reference to the Alvin and the Chipmunks franchise [especially their newly-made live action movies], and Eddie Murphy's The Fat Suit was a reference to his role as the Klump family in The Nutty Professor franchise.
In the Comic Book Store hangs a poster of Swatchmen, a parody of Watchmen.
The username I_Killed_Kenny6475 is a reference to the TV show South Park.
After the man that trained Homer falls down to the ground, he uses his shirt as wings to fly like Rocky the Flying Squirrel from The Rocky and Bullwinkle Show.
The title is a play on an old slogan of Burger King: "Home of the Whopper".
At the theater, Homer sees and scares Daffy Duck, a character from Warner Bros. Looney Tunes cartoons.
Worth note: Comic Book guy would not be able to completely independently publish Everyman, as the series contain references to other known comic books such as Plastic Man and Iron Man. He would at least have to get permission from Marvel and DC to use their characters.
Two comic book characters named Everyman actually does exist, one appearing in 1982's Captain America 267. While the other belongs to DC and first appeared in 52 #21.
The cover of the "controversial issue" of Every Man featuring the death of Marmaduke was taken directly from the cover of the Batman comic story A Death in the Family featuring the death of Jason Todd.
Comic Book Guy's Quote "I shall self-publish"" is a reference to the phrase said by Gandalf in The Lord of The Rings "You shall not pass!". both phrases are said in the same tone.