In the commentary it says that the Child Protective Services male officer was based on a teacher the writers had.
In the original airing, Milhouse mentioned the basket with the infected monkey in it came from Pier One. After Pier One complained about the joke, the reruns changed the line to Trader Pete's. Later syndicated reruns on FXX, as well as the season seven DVD version and the streams from FXX's official streaming site retain the original line, though the closed captioning/subtitles have the "Trader Pete" line instead of the "Pier One" line. In the UK, the Trader Pete line is used, as there are no Pier One stores over there.
In the parenting class, Agnes Skinner said that the state was threatening to take Seymour away because they had another fight over the inflatable bath pillow. They first fought over the bath pillow in the episode The Springfield Connection from the previous season.
It is revealed in this episode that Marge microwaves Bart and Lisa's underwear on cold days and Homer calls radio stations and gives them fake traffic hints.
Lisa comes home with trash bags on her feet, but Bart comes home wearing a potato sack and is barefoot. Unlike Lisa, Bart does not have prescription shoes.
Also, how did Lisa get her shoes back?
The social workers shouldn't have been able to take the kids away due to circumstantial evidence, and without questioning Marge and Homer.
Realistically, the kids would have been sent to separate foster homes.
Also, sending the kids in the Flanders' home violates the 100-foot restraining order that Homer and Marge were given against the children, and even if the restraining order wasn't in place, the kids shouldn't have been put in a foster home next door to their parent's home.
If Homer and Marge wanted to call the kids, they could have simply gone to a pay phone.
When playing a religious trivia game, Maggie somehow gets a question right despite being unable to talk, although this may have been done to emphasize Bart and Lisa's lack of knowledge of the topic. It is possible that she nodded her answer.
The Flanders have both "fire" and "police" on autodial, even though they are both 911.