Hiram was the first husband of Mabel Simpson, and they had one child, Eliza Simpson. The family worked with the underground railroad, helping slaves flee to Canada. Hiram, though, turned against his family and Virgil, one runaway slave under their care, by betraying Virgil to Colonel Burns. Mabel, however, fell in love with Virgil, left her husband, and helped Virgil escape to Canada where the two married and began the family tree from which the modern-day Simpsons descend. Through Eliza Simpson, he is an ancestor of the Van Houten family but not the modern Simpsons themselves. Since Virgil's position in the family is the great-great-great-great grandfather, it is possible that Hiram and Eliza are related to the generations from The Simpsons Uncensored Family Album that came before the Hiram-Virgil cutoff. According to Abe, his family kept Virgil's existence a secret to avoid racist remarks at the time, which they may have also tampered with the family tree (such as removing Hiram, Mabel and Eliza from the tree) to deny any affiliation with Virgil.