The Garden of Eden is a garden created by God.
Marge falls asleep in church in the episode "Simpsons Bible Stories". In her dream she saw that the garden housed Adam and Eve as well as many animals, such as Gary the Unicorn and the Pig of Eden. It also housed the forbidden tree. A serpent persuaded Eve to eat from the tree and as a result, Eve was flicked out. Adam was also flicked out for helping Eve back in.