The secret ingredient in the Flaming Homer and Flaming Moe: Krusty's Non-Narkotik Kough Syrup for Kids.
The knockoff's of Flaming Moe's that spring up overnight include Flaming Meaux, Flaming Moe's pushcart, and Famous Moe's.
The gang at Flaming Moe's include: Lenny, Carl, Barney, Krusty, Dr. Nick, Princess Kashmir, Ned and Maude Flanders, Jasper, Otto, Ms. Krabappel, Kent Brockman and Barney again.
A sign behind the bar reads, "Bartenders do it 'till ya barf".
Maggie says Moe in this episode - in Homer's hallucination. Whether or not it counts as her first word is up to you. Note that she also said It's your fault I can't talk! in Bart vs. Thanksgiving, which was also in a Simpson's imagination.
A bowie knife, a glass eye, a troll doll and the cough syrup are in the Lost and Found box.
Underneath the floorboards at Lisa's slumber party is a pipe labeled lead and insulation labeled Asbestos.
During the Eye On Springfield credits, a SPRINGFIELD can be seen spelled out in giant letters a la HOLLYWOOD sign. This is also seen in The Simpsons Movie and episodes afterwards (post Season 19).
Both names ascribed to the drink (Flaming Homer and Flaming Moe) are similar to terms for a stereotypical homosexual (flaming homo and flaming 'mo, respectively).
This is the only episode to make mention of a junior high (or middle) school in Springfield, as Moe complains that it being across the street is the only source of income for him due to the cigarette machine, although future episodes indicate that it was merely a reference since the opposite side of the street has had a gay bar called The League of Extra-Horny Gentlemen, a club for Springfield's elite and socialites, and even a motel.
The chalkboard gag implies that Bart wore his underwear on the outside. In Simple Simpson, Homer became a superhero whose costume consists of underwear on the outside.
Barney is greeted by everyone shouting his name as he walks into Flaming Moe's, in the same manner that Norm is greeted when he enters the bar in Cheers.
Moe's answer to Homer about where the waitress had gone is a reference to Shelley Long's decision to leave Cheers.
Homer's revelation of the drink's secret ingredient is an allusion to The Phantom of the Opera. The way he wore his bath robe over one side of his face may be a second reference to the 1986 musical by Andrew Lloyd Webber, in which the Phantom wore a mask that covered the right side of his face.