A category which lists characters beginning with their surnames from A-Z who have appeared in The Simpsons so far only once.
All items (3402)
S
- Sherri and Terri's Great-Aunt
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- S12
- S13
- Sad Kid
- Sad Kid's dad
- Sad Kid's mom
- Sailor
- Mr. Sakamoto
- Sales Coordinator Relative
- Saloon Bartender
- Sam (Postcards from the Wedge)
- Sam (senior)
- Sam Monroe
- Sam Munroe
- Brt Sampsan
- Homar Sampsan
- Leezuh Sampsan
- Maagi Sampsan
- Marj Sampson
- Samuel Morse
- Samuel T. Duff
- Sancho Hernandez
- Sandra (Homerpalooza)
- Sandy
- Sapphire Lounge Guy
- Sarah Plain & Tall
- Sarah Silverman (character)
- Sardonicus
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- Saucer-men
- Saul Bernstein
- Saxophonist
- School Photographer
- Arnold Schwarzenegger
- Scoey (Music Conductor)
- Scoey’s killer
- Hank Scorpio
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- Scottish Rioter
- The Scoutmaster
- Scraps (Weekend at Burnsie's)
- Scratchy mascot
- Screamatorium Worker
- Screaming Woman
- Screwy
- Script Coach
- Dana Scully
- Mr. Seckofsky
- Security Guard 1 (Homerpalooza)
- Security Guard 1 (Lisa the Greek)
- Security Guard 2 (Homerpalooza)
- Security Guard 2 (Lisa the Greek)
- Sedan Bot
- Seething Sisters chef
- Seething Sisters owner
- Seething Sisters waitress
- Selma's Lovebot
- Senior Dance Instructor
- Sepulveda
- Serak the Preparer
- Seraphim
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- Sergeant Crew
- Serious Homer
- Serpent
- Serpent (character)
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- Sex Toy
- Sexy Assistant
- Señor Fritatta
- Shadow Knight
- Shasta
- Shavings owner
- She's the Fastest
- She-Wolf
- Sheila Chow
- Shelby
- Shelby's Father
- Shelbyville Abe
- Shelbyville boy
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- Shelbyville lemonade boy's brother
- Shelbyville Martin
- Shelbyville Milhouse's dog
- Shelbyville Nelson
- Shelbyville Sharks
- Sheldon
- Sheriff
- Sherman
- Sherman from IT
- Sherpas
- Sherri and Terri's cousin
- Shifty-Eyed Dog
- Shocked Woman
- Shortcake Chef
- Shoshanna
- Sick Japanese Worker
- Sid Vicious
- Sideshow Bomb
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- Sideshow Chicken
- Sideshow Raheem
- Sigur Rós (characters)
- Sigrín Siguðardóttir
- Long John Silver
- Beatrice Simmons
- Simon (cameraman)
- Simon Cowell (character)
- Simon Stoolowitz
- Abbey
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- Bart Simpson, Jr.
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- Bob Simpson
- Bonita Simpson
- Great-Uncle Boris
- Brit Simpson
- Claretta Simpson
- Cyrus Simpson
- Eliza Simpson
- Floyd Simpson
- Cousin Francine
- Galston Simpson
- Garwood Simpson
- Hiram Simpson
- Homer Simpson (Police Cops)
- Howland Simpson
- Hugo Simpson II
- Ivy Simpson
- Lambert Simpson
- Lily Simpson
- Lotus Simpson
- Mabel Simpson
- Magpie Simpson
- Marnie Simpson
- "Old Tut" Simpson
- Omar Simpson
- Pippa Simpson
- Prudence Simpson
- Rupert Simpson
- Sven Simpson
- Twitta Simpson
- Trixie Stemple
- Tyrone Simpson
- Valerie Togasaki-Rothman
- Vern Simpson
- Virgil Simpson
- Zeke Simpson
- Simpsons Family Lookalikes
- Singing Girl
- The Singing Hobo
- Singing Trout
- Single Worker
- Singles, Seniors, Childless Couples And Teens And Gays Against Parasitic Parents
- Sir Galahad
- Sir Nederick Flanders
- Sister Marilyn
- Sister Thomasina
- Sit 'n' Weep psychologist
- Site Manager
- Six People at McClellan's International
- Skeptical Teacher
- Skin Mites
- Headmaster Skinnedwiener
- Seymour Skinner (real)
- Skipper
- Skull and Crossbones Man
- Slarg Fish
- Wayne Slater
- Slava
- Sleazy Sam
- Sleep-Eazy Clerk
- Sleve McDichael
- Slightly Creepy Boy
- Slimu
- Slithers
- Sloan
- Slow Leonard
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-
- Smiley
- Stan Smith
- Smithsonian Guard 1
- Smithsonian Guard 2
- Smoker
- Snack Clerk
- Snake Jailbird (The Serfsons)
- Snake's Relative
- Snooze
- Snow Mom
- Snowball III
- SNPP Applicant
- SNPP Clerk
- SNPP Guard
- SNPP Security Guard
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- Socrates
- Solar Panel
- Big Solar (character)