Alvarine Gurney (née Bisque) was the mother of Jacqueline Bouvier and the maternal grandmother of Marge, Patty and Selma Bouvier. she is also the maternal great-grandmother of Bart, Lisa and Maggie. she is also the grandmother-in-law of Homer Simpson.
- Episode – "Fear of Flying" (flashback)
- Episode – "Homer's Phobia " (possibly mentioned)
- Book – The Simpsons Uncensored Family Album