Groundskeeper Willie, teaching French class, calls the students " cheese-eatin' surrender monkeys." The phrase has since entered the pop-culture lexicon, and it gained a lot of notoriety in the events leading up to the Iraq War.
On the Gracie Films logo, there is a saxophone version of the music.
This episode contains a clip form " Moaning Lisa", when Lisa meets Murphy.
This episode was the first in which a recurring character was killed off, something the staff felt that it would be a great storyline, with a lot of emotions.
The crew planned on Bleeding Gums Murphy, although Mike Reiss stated "I had been polling for years to kill Marge's mom, but this was a better idea."
Mike Reiss's father, a doctor, was the medical consultant on this episode. He stated that it was not possible to get appendicitis from eating a piece of metal.
This was one of two episodes in season 6 that was created with the help of the staff of , with the other being " The Critic A Star is Burns."
The shot of Grampa listening to Bleeding Gums's album on the wireless is recycled from " Homer's Barbershop Quartet".
In this episode, we find out that Bleeding Gums Murphy could be possibly related to Dr. Hibbert. He states "I had a younger brother who grew up to be a doctor. He used to laugh at the most inappropriate times." Hibbert then replies with "Hey, I have an older brother that I'll never see. He's a jazz musician or some such."
This is the first episode to feature a Simpson getting an organ permanently extracted.
The title is a play on " 'Round Midnight" by Thelonious Monk and the film .
Round Midnight Homer has a Starland Vocal Band tattoo on his arm.
The music just before Bart's operation is a parody of the theme music of .
ER Bart's showing off his appendectomy scar (which prompts a number of other children to want the operation) is reminiscent of the children's book : Madeline has her appendix out, says her favorite thing about the experience is her scar, and the rest of the girls in her school want to have their appendixes out as well.
Madeline When Bleeding Gums Murphy tells Lisa about his career, he mentions guest spots on (when The Tonight Show Steve Allen was hosting) and on .
The Cosby Show According to the banner in front of Springfield Elementary School, Barbra Streisand is playing the night after the recital, and tickets are still available. The recital, however, is sold out.
When Bleeding Gums Murphy appears to Lisa near the end he is joined by Darth Vader, Mufasa, and James Earl Jones (saying "This is CNN").
Although all three roles were portrayed by Jones, the characters in this scene were voiced by Harry Shearer.
Additionally, Mufasa accidentally mentions "Kimba" and corrects himself by saying " Simba." This is a reference to the debate regarding The Lion King's resemblance to the anime .
Kimba the White Lion Robert Shaporo and Albert Dershman are parodies of attorneys Robert Shapiro and Alan Dershowitz.
Lisa and Bleeding Gums play Carole King's song " Jazzman" twice.
When Lisa asks to jam "One more time!", Bleeding Gums protests that he's got a date with Billie Holiday.
Barney's attempt to get a drink at Moe's for an AA chit is a reference to a popular legend that these can be cashed in at bars.
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